Effect of Aerobic Versus Resistive Exercise on Cardiac Functions in Patients with Hypothyroidism

Document Type : Original Article

Authors

1 B.SC in physical therapy, Cairo UniversityB.SC in physical therapy, Cairo University

2 Professor of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University

3 MD internal Medicine (Alex.), Consultant internal Medicine, Ministry of Health

4 Assistant professor of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University

10.21608/iptccu.2025.438012

Abstract

Background:
Hypothyroidism results from a reduction in thyroid hormone levels, either due to decreased endogenous synthesis or exogenous hormone administration. Physical training has been shown to enhance endothelial function in individuals with hypothyroidism. Furthermore, physical exercise plays a role in mitigating obesity commonly associated with hypothyroidism, given that thyroid hormones regulate metabolic processes. Additionally, both aerobic and resistance exercise contribute to an increase in blood HDL cholesterol levels and have a positive impact on overall quality of life. Purpose: to compare the effect of Aerobic and resistive exercise on cardiac function in patient with hypothyroidism. Patients and Methods: Fifty-two hypothyroidism patients from both sexes, their age ranged from 40 to 50 years were selected from outpatient clinic of the Internal Medicine Department at Edko Central Hospital. They were randomly assigned into two groups (26 each): Group A (Aerobic group) and Group B (Resistive group). Outcome measures: Cardiac function through assessing (ejection fraction and Cardiac Index), Thyroid hormones levels (TSH, T3, T4), and health related quality of life by using SF-12 questionnaires after three times per week for 12 successive weeks. RESULTS: There was a significant variation in EF, CI, TSH, Physical Function, Vitality, Social Functioning, Role Emotional, Mental Health between both groups post-treatment (P= 0.005), with no significant variation in T3, T4, General Health, Role Physical, Body Pain). Conclusions: Aerobic exercise and resistance exercises had good effect in controlling thyroid function through improving TSH, T3, and T4 level, cardiac functions that leading to improve the quality of life in hypothyroidism patient.

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